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When you choose to publish with PLOS, your research makes an impact. Make your work accessible to all, without restrictions, and accelerate scientific discovery with options like preprints and published peer review that make your work more Open.

Exciting new cellular and molecular biology research

PLOS Biology is home to high quality, original research with a broad scope across the biological sciences. We empower authors to share and get credit for their work and offer publishing options that boost the visibility of your science.

The biology of extracellular vesicles: The known unknowns

Leonid Margolis, Yoel Sadovsky

UNSOLVED MYSTERY


Over a century of cancer research: Inconvenient truths and promising leads

Carlos Sonnenschein, Ana M. Soto

ESSAY


A proteomic atlas of senescence-associated secretomes for aging biomarker development

Nathan Basisty, Abhijit Kale, Ok Hee Jeon, Chisaka Kuehnemann, Therese Payne, et al
Methods & Resources

Published peer review history


Islands of retroelements are major components of Drosophila centromeres

Ching-Ho Chang, Ankita Chavan, Jason Palladino, Xiaolu Wei, Nuno M. C. Martins, et al

RESEARCH ARTICLE


Snail synchronizes endocycling in a TOR-dependent manner to coordinate entry and escape from endoreplication pausing during the Drosophila critical weight checkpoint

Jie Zeng, Nhan Huynh, Brian Phelps, Kirst King-Jones
RESEARCH ARTICLE

Primary cilium loss in mammalian cells occurs predominantly by whole-cilium shedding
Mary Mirvis, Kathleen A. Siemers, W. James Nelson, Tim P. Stearns
SHORT REPORT

A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation
Kotaro Tsuboyama, Tatsuya Osaki, Eriko Matsuura-Suzuki, Hiroko Kozuka-Hata, Yuki Okada, et al
RESEARCH ARTICLE
Published peer review history

CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
Christopher J. Shoemaker, Tina Q. Huang, Nicholas R. Weir, Nicole J. Polyakov, Sebastian W. Schultz, Vladimir Denic
METHODS AND RESOURCES


LOOKING AHEAD

The future of PLOS Biology

Nonia Pariente, on behalf of the PLOS Biology Staff Editors

Editorial

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